Dr Tom Mules is a physician specialising in gastroenterology and hepatology, and lecturer at the University of Otago School of Medicine. His research interests include the role of intestinal barrier dysfunction in disease, hookworm therapy, Helicobacter pylori and the psychosocial impact of inflammatory bowel disease.
Tom is part of the Hookworm therapy programme in the Le Gros Laboratory.
Related news
RNZ Our Changing World: Targeting bacteria, and health inequities
4 July 2024
Double doctor: exceptional thesis awarded to Malaghan gastroenterologist
5 June 2024
New clinical research aims to reduce stomach cancer rates and disparities in New Zealand
28 May 2024
In Focus: Could eradicating a bacterial infection be the key to preventing stomach cancer?
8 February 2024
‘Infect and forget’: Hookworm study sets groundwork for medication-free management of inflammatory bowel disease
16 June 2023
Could a dose of worms be the answer to treating incurable autoimmune diseases?
14 November 2021
Publications
2024
Noble SL, Mules TC, Le Gros G, Inns S (2024). The immunoregulatory potential of eosinophil subsets. Immunol Cell Biol. 102(9):775-786.
Noble SL, Vacca F, Hilligan KL, Mules TC, Le Gros G, Inns S (2024). Helminth infection induces a distinct subset of CD101hi lung tissue-infiltrating eosinophils that are differentially regulated by type 2 cytokines. Immunol Cell Biol. 102(8):734-746.
Mules TC, Tang JS, Vacca F, Yumnam B, Schmidt A, Lavender B, Maclean K, Noble SL, Waugh C, van Ginkel R, Camberis M, Le Gros G, Inns S (2024). Modulation of intestinal epithelial permeability by chronic small intestinal helminth infections. Immunol Cell Biol. 102(5):396-406
2023
Mules TC, Inns S, Le Gros G (2023). Helminths' therapeutic potential to treat intestinal barrier dysfunction. Allergy. 78(11):2892-2905
Mules TC, Lavender B, Maclean K, Vacca F, Noble SL, Yumnam B, Te Kawa T, Cait A, Tang J, O'Sullivan D, Gasser O, Stanley J, Le Gros G, Camberis M, Inns S (2023). Controlled Hookworm Infection for Medication-free Maintenance in Patients with Ulcerative Colitis: A Pilot, Double-blind, Randomized Control Trial. Inflamm Bowel Dis. 2023 Jun 15